From Wikipedia
The Great Fire of Rome (Latin: Magnum Incendium Romae) was a large fire which struck ancient Rome in 64 AD. According to the historian Tacitus, the fire started on the night of 18 July, among the shops clustered around the Circus Maximus. As many Romans lived in wood houses without masonry, the fire spread quickly through these areas. The fire was almost contained after five days before regaining strength. The historian Suetonius claims the fire burned for six days and seven nights in total. The fire destroyed three of fourteen Roman districts and severely damaged seven, while leaving only four undamaged. Also destroyed were Nero's palace, the Temple of Jupiter Stator and the hearth in the Temple of Vesta.
