From Wikipedia

Lost Cities Of The Inca

The Inca civilization began as a tribe in the Cuzco area, where the legendary first Sapa Inca, Manco Capac founded the Kingdom of Cuzco around 1200. Under the leadership of the descendants of Manco Capac, the Inca state grew to absorb other Andean communities. In 1442, the Incas began a far-reaching expansion under the command of Patchacuti. He founded the Inca Empire (Tawantinsuyu), which became the largest empire in pre-Columbian America.

The empire was split by a civil war to decide who would be Inca Hanan and who would be Inca Hurin (Hanan and Hurin represent the families of the higher parts of the city (Hanan) and those of the lower parts (Hurin) it is believed that one of the brothers was from Hanan Cuzco and the other from Hurin Cuzco as they where part of the family of their mothers), which pitted the brothers Huascar and Atahualpa against each other. In 1533, Spanish Conquistadores led by Francisco Pizarro, took advantage of this situation and conquered much of the existing Inca territory. In succeeding years, the invaders consolidated power over the whole Andean region, repressing successive Inca resistance and culminating in the establishment of the Viceroyalty of Perú in 1542. The militant phase of Inca liberation movements ended with the fall of resistance in Vilcabamba during 1573. Though indigenous sovereignty was lost, Inca cultural traditions remain strong among surviving indigenous descendants such as the Quechuas and Aymara people.